Executive function, mentalizing and humor in major depression

Executive function, mentalizing and humor in major depression.

Major depression is associated with cognitive deficits including memory, executive functions, and affect perception, which have been linked to dysfunction of fronto-subcortical networks. However, little is known about social cognition on more complex socially relevant tasks, such as humor processing. In this investigation a computerized humor-processing task was administered to 27 patients with...

Executive function impairments in patients with depression.

Depression, the most prevalent psychiatric disorder, has a lifelong risk of 20% and is related to high rates of death among the patients. Thus, this study aims to conduct a systematic review of changes in executive functions of adult patients diagnosed with depression. We found 1381 articles; however, only 28 were selected and recovered. The inclusion criteria was the assessment of executive fu...

A study of recurrent unipolar major depression and executive functions

Reduced hippocampal volume correlates with executive dysfunctioning in major depression.

OBJECTIVE Dysfunction of neuronal plasticity or remodelling seems to contribute to the pathopysiology of major depression and may cause the well-documented hippocampal changes in depression. We aimed to investigate whether reduced hippocampal volumes correlate with executive dysfunctioning or memory dysfunctioning or with depression severity. METHODS We recruited 34 inpatients with a previous...

Executive dysfunction in schizophrenia and its association with mentalizing abilities.

INTRODUCTION Patients with schizophrenia have been found impaired in important aspects of their basic and social cognition. Our aim in this study is to explore the relationship between executive function (EF) and theory of mind (ToM) deficiencies in patients that suffer the illness. MATERIALS AND METHODS Twenty-two Spanish-speaking inpatients and 22 healthy controls matched in age, sex, educa...